
Trimethoprim Lactate ReadyMade™ Solution
SKU: T1012-20ml
Key Benefits
- ReadyMade™ formulation for immediate use, eliminating preparation steps and ensuring consistent performance
- Potent inhibitor of bacterial DHFR and folate metabolism
- Enables synergistic antibacterial effects when combined with sulfonamides
- Widely used in metabolic and antimicrobial research
- High consistency for reproducible experimental outcomes
OptionAvailabilityPrice
- Size(ml): 20Out of Stock€ 99,90
Trimethoprim lactate is a synthetic diaminopyrimidine antibiotic widely used in microbiology and molecular biology research. It exhibits antibacterial activity by selectively inhibiting bacterial dihydrofolate reductase (DHFR), a key enzyme in folate metabolism. Trimethoprim is commonly used alone or in combination with sulfonamides such as sulphamethoxazole to achieve synergistic inhibition of bacterial growth.
Mechanism of Action:
Trimethoprim selectively inhibits bacterial dihydrofolate reductase (DHFR), preventing the reduction of dihydrofolic acid to tetrahydrofolic acid. This disrupts the synthesis of nucleotides and ultimately inhibits DNA, RNA, and protein synthesis.
When combined with sulfonamides, trimethoprim provides a sequential blockade of folate biosynthesis, resulting in enhanced antibacterial efficacy.
Product Details
| Property | Value |
|---|---|
| Primary Category | Research+Reagents |
| Secondary Category | DNA/RNA Inhibitors |
| Key Feature | Folate |
| CAS.NO. | 23256-42-0 |
| Solvent | Water |
| Concentration | 20 mg/ml |
Note
For research use only. Not for diagnostic or therapeutic use.
Safety Data Sheets
T1012 Trimethoprim Lactate Solution A0Download PDF