
Mercaptopurine Monohydrate ReadyMade™ Solution
SKU: M1501-20ml
Key Benefits
- ReadyMade™ formulation for immediate use, eliminating preparation steps and improving reproducibility
- Potent inhibitor of purine metabolism and nucleic acid synthesis
- Widely used in cell proliferation and apoptosis studies
- Suitable for genetic selection systems such as HGPRT-based assays
- High consistency for reproducible experimental outcomes
OptionAvailabilityPrice
- Size(ml): 20Out of Stock€ 99,90
Mercaptopurine monohydrate (6-mercaptopurine, 6-MP) is a thiopurine analog widely used as an antimetabolite in molecular biology and cell biology research. It interferes with purine nucleotide metabolism and is commonly used to study DNA synthesis, cell proliferation, and apoptosis. Mercaptopurine is also used in genetic selection systems, particularly in combination with hypoxanthine-guanine phosphoribosyltransferase (HGPRT)-based selection.
Mechanism of Action:
Mercaptopurine is converted intracellularly into active thioguanine nucleotides, which inhibit de novo purine synthesis and become incorporated into DNA and RNA. This disrupts nucleic acid synthesis and function, ultimately inhibiting cell proliferation and inducing cell death.
Product Details
| Property | Value |
|---|---|
| Duchefa No. | M0129 |
| Primary Category | Research+Reagents |
| Secondary Category | DNA/RNA Inhibitors |
| Key Feature | Purine analog |
| CAS.NO. | 6112-76-1 |
| Solvent | 70% Ethanol |
| Concentration | 0.2 mg/ml |
Note
For research use only. Not for diagnostic or therapeutic use.
Safety Data Sheets
M1501 Mercaptopurine Monohydrate Solution A0Download PDF