Colistin Sulphate ReadyMade™ Solution

SKU: C1083-20ml

Key Benefits

ReadyMade™ formulation for immediate use, reducing preparation time and improving consistency
Strong activity against Gram-negative bacteria, including multidrug-resistant strains
Effective tool for studying bacterial membrane integrity
Suitable for selective isolation of Gram-negative organisms
High consistency for reproducible experimental results

OptionAvailabilityPrice

Size(ml): 20Out of Stock€ 99,90

Colistin sulphate (polymyxin E) is a cyclic polypeptide antibiotic belonging to the polymyxin class, originally isolated from Paenibacillus polymyxa. It exhibits potent activity against Gram-negative bacteria, particularly Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter species. Colistin is widely used in microbiology as a selective agent for Gram-negative bacteria and as a tool for studying membrane integrity and antibiotic resistance. Mechanism of Action: Colistin Sulfate displaces essential ions (magnesium and calcium) in the lipopolysaccharide layer of the cell wall leading to local disturbance of the outer membrane, which causes increased permeability and eventually cell lysis. Colistin also has anti-endotoxin activity. The endotoxin of Gram-negative bacteria is the lipid A portion of the lipopolysaccharide molecules, and colistin binds and neutralizes the lipolysaccharide (Falagas et al, 2005).

Product Details

Property	Value
Duchefa No.	C0118
Primary Category	Antimicrobials
Secondary Category	Antibiotics
Key Feature	Membrane
CAS.NO.	1264-72-8
Solvent	Water
Concentration	50 mg/ml

Note

For research use only. Not for diagnostic or therapeutic use.

Safety Data Sheets

C1083 Colistin Sulfate Solution A0Download PDF

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